The 9 Best VC Firms In Raleigh, NC [2022]

The 9 Best VC Firms In Raleigh, NC [2022]

Are you looking for a VC Firm in Raleigh, NC?

Finding the right VC firm for your startup can be a daunting task.

There are a number of successful VC Firms in Raleigh, and we've curated a list of the best VC firms in the area.

Here's the list:

1. Rex Health Ventures

  • Location: Raleigh, NC
  • Industries: Healthcare
  • Investment Range: ~$10M - $50M
  • Stage: ~Series B
  • Companies invested in: ~Phynd, Arrivo, Veran

Rex Health Ventures (RHV) supports innovative work and invests in companies working towards the advancement of healthcare.

RHV helps in the discovery and growth of new treatments, products, tools, and services to have a positive impact on the healthcare industries all around North Carolina and the U.S

They typically invest anywhere from $10M - $50M.

Learn more about Rex Health Ventures ➜


2. Southern Connection Ventures

  • Location: Raleigh, NC
  • Industries: Financial Technologies, Digital Health, B2B and B2C, IoT, Digital Media
  • Investment Range: ~Not disclosed
  • Stage: ~Seed Stage
  • Companies invested in: ~Toucan AI, Owl Insights, Blueberry Pediatrics

Southern Connection Ventures' Angel Network connects investors and advisors with the best graduate & undergraduate students in the South. They allow their Angel Network to hand-pick well-managed early-stage venture investments and advisory roles.

Their Angel Network has successful entrepreneurs and early, mid, and late-career business professionals who want to support early-stage investments.

Learn more about Southern Connection Ventures ➜


3. Southern Capitol Ventures

  • Location: Raleigh, NC
  • Industries: Software, E-commerce, Digital Media, Healthcare, IT,and Mobile Companies
  • Investment Range: $35K - $1M
  • Stage: Seed Stage
  • Companies invested in: AdWerx,, Zift Solutions

Since its launch in 2000, Southern Capitol Ventures is focused on helping exceptional entrepreneurs build prominent companies.

They have a very disciplined investment strategy and while they focus on early-stage companies, they also consider later-stage opportunities.

Their typical investments range from $35k - $1M initially.

Learn more about Southern Capitol Ventures ➜


4. Harbright Ventures

  • Location: Raleigh
  • Industries: Software, Technology, Services, Healthcare, Industrial
  • Stage: ~Seed Stage
  • Companies invested in: ~Ascyrus Medical LLC, Proaxion

Harbright Ventures is an early-stage investor based in Raleigh-Durham with a team of highly experienced & talented members. They are always looking for opportunities to create value with entrepreneurs and bring positive change to businesses across the world.

Learn more about Harbright Ventures ➜


5. Oval Park Capital

  • Location: Raleigh, NC
  • Industries: Technology, Enterprise Software
  • Investment Range: $500K - $1.5M
  • Stage: Seed Stage
  • Companies invested in: NALA Systems, Applied Life Sciences & Systems, Medicom Technologies

Oval Park Capital is an early-stage venture capital firm that focuses on technology and enterprise software startups in the Southeast US.

They conduct a rigorous screening process to create long-term value and accelerate portfolio company growth.

They typically invest anywhere from $500K - $1.5M.

Learn more about Oval Park Capital ➜


6. Cherokee Investment Partners

  • Location: Raleigh, NC
  • Industries: Real Estate, Environmental, Energy
  • Investment Range: $1M-$5M
  • Stage: Series A
  • Companies invested in: Savii Inc.

Cherokee is an investment company with the purpose to blend capital with creativity and experience for investors, partners, and communities.

Cherokee makes investments in both venture capital and equity to create more value for all involved.

They typically invest anywhere from $1M - $5M

Learn more about Cherokee Investment Partners ➜


7. One Better ventures

  • Location: Raleigh, NC
  • Industries: Mission-driven Companies with Brands, Products, Business Models and Teams
  • Investment Range: $5M-$20M
  • Stage: Series B
  • Companies invested in: Evergreen Media, Grove, FBOMB

One Better Ventures partners with extraordinary entrepreneurs to unleash their true potential and build community.

They are a deeply committed enterprise that provides corporate citizenship in their community.

They typically invest anywhere from $5M - $20M

Learn more about One Better ventures ➜


8. River Cities Capital Funds

  • Location: Raleigh, NC
  • Industries: Healthcare and Technology
  • Investment Range: $5M-$20M
  • Stage: Series B
  • Companies invested in: Standard Bariatrics, BardyDx, Q'apel

River Cities is a renowned growth equity firm that invests in high-potential healthcare and technology companies. They aspire to be a business partner first and foremost and a capital provider second.

In the past 27 years, they have raised more than $750 million of capital and have built a consistent track record of success.

They typically invest anywhere from $5M - $20M

Learn more about River Cities Capital Funds ➜


9. Sherpa Collaborative

  • Location: Raleigh, NC
  • Industries: Consumer Products
  • Investment Range: $25k - $50K
  • Stage: Seed Stage
  • Companies invested in: Slingshot Coffee Co., Leesa, Lawson Hammock

Sherpa Collaborative thrives in the start and the launch phase of any business.

Their efficient team has found and led many businesses from inception to growth. They acquire diverse skill sets and can assist with a broad spectrum of startup requirements.

Their typical investment range is $25k - $50k

Learn more about Sherpa Collaborative ➜


10. NovaQuest Capital Management

  • Location: Raleigh, NC
  • Industries: Life Sciences and Healthcare
  • Investment Range: Not disclosed
  • Stage: Series B
  • Companies invested in: Allergan, CoreRx, Azurity

NovaQuest Capital Management helps in the development of healthcare technologies and life-saving drugs to improve the overall quality of life.

The firm is based out of Raleigh and it invests in the growth of next-gen drugs, technologies and services.

Learn more about NovaQuest Capital Management ➜

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