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Lisa started housepaws in 2010. They detail the beginnings of their company in their Starter Story interview: 
Q: How did you get started on housepaws?
I ALWAYS wanted to be a vet. There was no other option. When I was in high school I would read the stories of James Herriot who was a traveling vet who did large and small animals. I thought the idea of doing this was serene and romantic but not practical in this day and age.
Once my husband and I started our own family we decided to have midwives and have our children at home. Those experiences made me realize you can do good quality medicine in the comfort of one's own home. If you can do it for people why not pets? I watched technology change and people wanted more convenient services and I thought it was the perfect time to try going mobile. As I was researching how to create a mobile vet practice I got released from my job. That was the catalyst that made things develop full throttle. I went to a local networking meeting and walked out with an attorney, an insurance agent, a car wrapping company, and an accountant. Within a week I had an LLC, business insurance, and was ready to roll to my first appointment.